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Jeffrey James Weise (August 8, 1988 – March 21, 2005) was an American student at Red Lake Senior High School in Red Lake, Minnesota, who committed the Red Lake shootings on March 21, 2005.
On March 21, 2005, Weise killed his grandfather and his grandfather's companion before going to the reservation high school, where he murdered seven more people and wounded five others. He died by suicide before he could be captured by the police. Weise struggled in school due to frequent relocations, bullying, disruptions in his personal life and truancy.
In May and June 2004, Weise attempted suicide and was briefly hospitalized. He was under treatment for depression, and had been prescribed Prozac as an anti-depressant. His case revived the public discussion about the use of Prozac for children and adolescents; the Food and Drug Administration had published a warning about it in October 2004 as a factor in increased suicides and violence among youths.